E9E +S ES E + P, where E is the enzyme, P is the product, and S is the substrate (Kumar, C. 2011). For an enzyme that is specific, one substrate molecules may bind in the required way to give out a function of the EES complex. On the other hand, the substrate needs to have a shape, size, and polarity that is compatible with the active enzyme site (Witkop, C. 2009). Other enzymes may catalyze the many different molecules transformation whenever there exists a common category of a chemical linkage of the given substrate. Some have specificity hence can form ES complexes that are reactive having one structure of a molecule.